I drive a subcompact, korean hatchback in an orangey red colour that has the girliest horn I've ever heard; not the least bit manly. It does do its job though, it gets me around reliably and cheaply.
I've owned and driven "masculine" vehicles, a old lifted ford that looked like it had just been unearthed, a F350 crewcab 4x4 (not actually that imposing or impressive despite what some think), and a couple of big 70s land yachts.
But I've also owned a Ford Festiva, a 1965 Beetle and two 1970s' VW busses.
The only difference on the road is that people are more willing to give way to a more imposing vehicle compared to a "girly" car. But that being said the most positive comments and feedback on any vehicles I've owned have been on the air-cooled VWs.