I like Scotland very much, visit it atleast once a year.
If breathtaking scenery combined with history in an active vacation is your thing, you can't go wrong with Scotland.
If on the other hand your perfect getaway is a cocktail on a beach for 2 weeks, look elsewere.
Things to see? The Highlands! (pretty much everything West of the Caledonian canal).
I find the north to be the most remote and beautifull part for a 2/3 day driving tour (bar example): start in Inverness (shithole) and drive all the way North to Jhon O Groats, make sure to stop in Wick and have a drink at the Nethercliff pub, From Jhon O Groats head West and just keep on the main road to Durness, then head south to a little place called Scourie, it's a little hamlett nesteld in a cove....remote as all hell but very pleasant.
Lower down we have what are considerd the West highlands, and offcourse the Isle of Sky, witch is another must see, very beautifull, if a tad touristy.....you can't go wrong in the highlands realy.
Loch ness....yes you knew it was coming, it's a rather ugly Loch (as compared to some others) that isen't even realy a loch, it has several tourists centers around it selling stuffed nessies, and yet I find myself visiting it every time I'm in the highlands.....For one reason: Fort Augustus is a small town on the most southern part of the lake, 2 pubs, few hotels and a handfull b&b's, I concider it my second home.
On your way to Edinburgh and the lowlands take the A82 from Fort William, the pass of the Clenncoe is a nice view, further east Stirling is an exellent place to stop, plenty of historical things to see and do depending on your intrests, come to think of it so is most of that part of Scotland.
Edinburgh is another must do, granted not the most pleasant city in the world, and 'the royal mile' is an overcrowded tourist trap filled with Pakistanies trying to sell you fake kilts, but Edinburgh Castle is awesome, and the arcitecture in the centre is very nice....there are also a gazillion ways to get drunk.
Scotland in General is a nice place if you know what to avoid, that's why I avoid most of the bigger cities except Edinburgh as I prefer small 1 horse towns, nothing like arriving someswhere in the afternoon after driving and seeing some fantastic scenery, throwing your bag down on the bed in the b&b, and go see the local sights till nightfall, then find a pub, have a few drinks, mix with the locals (who are surprisingly hospitable, often more then willing to talk about the area and point you towards local 'secret' beautyspots) and go to bed.
Food is of the heartkilling 'I wonder how many cows went into that' kind, alcohol is everywhere and cheap, if you like Scotch, you could spend several months doing nothing but visiting distillies and tastings.
Don't be surprised if you walk into a tiny pub in a tiny town and find 50 different Whisky's behind the counter....they probably have more out back as they ran out of shelfspace.
I'm 'plotting' driving trips to Scotland for people all the time, if you decide to go give me a shout, I will be more then happy to put something together for you depending on you and your wifes intrests.